Houston Gaines (R) defeated Jeff Baker (R) and Ryan Millsap (R) in the Republican primary for Georgia's 10th Congressional District on May 19, 2026. Gaines and Millsap led the candidate field in local media attention.

Incumbent Mike Collins (R) ran for U.S. Senate rather than seeking re-election. As of the primary, major election forecasters rated the general election Solid/Safe Republican. In the 2024 election, Collins defeated Lexy Doherty (D) 63.1%–36.9%.

As of the 2026 primary, Gaines was director of business development at Carter Engineering. He was elected to the Georgia House in 2022. The Atlanta Journal-Constitution's Greg Bluestein wrote that Gaines was "[a] close ally of [Gov. Brian] Kemp...[who] has helped steer GOP priorities on crime and prosecution, including a 2023 law giving the state new powers to oust local prosecutors and hard-line immigration crackdowns after the killing of Laken Riley." After Millsap entered the race, Gaines said, "Our district isn't for sale to a California film executive. We've had enough of Hollywood in Georgia."

Millsap was, as of the 2026 primary, the founder and chief executive officer of Indira Capital Management, a real estate investment firm. He earlier served as chairman and chief executive officer of Shadowbox Studios, an Atlanta-area film studio. Millsap said he was running "because we need someone with a titanium backbone who doesn't care about climbing the political ladder but is running to defeat the radical left once and for all and end the reign of radical lunatic liberals and impotent RINOs in Congress."

If no candidate had won more than 50% of the vote, the top two finishers would have advanced to a June 16 runoff.