Deborah Peoples and Mattie Parker advanced to a runoff from a 10-candidate field in the nonpartisan general election for mayor of Fort Worth, Texas, on May 1, 2021. Peoples received 33.6% of the vote and Parker received 30.8% of the vote. Brian Byrd, the third-place finisher, received 14.7% of the vote. The runoff election will take place on June 5.

Incumbent Mayor Betsy Price announced on January 5, 2021, that she would not run for re-election. Mayoral elections in Fort Worth are nonpartisan, meaning candidates appeared on the ballot without party affiliations. 

Peoples is the Chair of the Tarrant County Democratic Party and previously worked as a business executive. She was endorsed by U.S. House Rep. Eddie Bernice Johnson (D), The Collective PAC, Grassroots Law Project, and Higher Heights PAC. As of April 21, she raised $286,180 and spent $238,351.

Parker is an educator and previously worked as the chief of staff for the Fort Worth Mayor and City Council. She was endorsed by Mayor Price, former Mayor Mike Moncrief, the Fort Worth Star-Telegram, and The Dallas Morning News. As of April 21, she raised $1,033,304 and spent $834,823.

Ann Zadeh, Daniel Caldwell, Mylene George, Mike Haynes, Cedric Kanyinda, Steve Penate, and Chris Rector also ran in the election. They made up the largest mayoral candidate field in at least a decade.